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Anti-Human CEP63 Polyclonal Antibody (HD664014)

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Vista general
Número de catálogoHD664014
Descripción
Anti-Human CEP63 Polyclonal Antibody (HD664014) is a rabbit polyclonal antibody detecting CEP63. Suitable for Human.
Reactividad de especiesHuman
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human CEP63 (Met1-Ile309).
Objetivo CEP63, Centrosomal protein of 63 kDa, Cep63
Nivel de endotoxinas Please contact with the lab for this information.
Purificación Purified by antigen affinity column.
Número de acceso Q96MT8
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Fondo

Centrosomal protein of 63 kDa (CEP63) is a ~81 kDa protein. Required for normal spindle assembly. Plays a key role in mother-centriole-dependent centriole duplication; the function seems also to involve CEP152, CDK5RAP2 and WDR62 through a stepwise assembled complex at the centrosome that recruits CDK2 required for centriole duplication. Reported to be required for centrosomal recruitment of CEP152; however, this function has been questioned. Also recruits CDK1 to centrosomes. Plays a role in DNA damage response.

1. Löffler, H. et al. (2011) Cancer research 71, 2129-39. PMID: 21406398
2. Sir, JH. et al. (2011) Nature genetics 43, 1147-53. PMID: 21983783
3. Kodani, A. et al. (2015) eLife 4. PMID: 26297806
4. Kodani, A. et al. (2022) EMBO reports 23, e52211. PMID: 35793002
5. Ling, H. et al. (2022) Oncogene 41, 4433-4445. PMID: 35989368
Nota For research use only
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
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Concentration
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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