Human CEP63 Recombinant Protein (N-His) (HD664012)

Name: Human CEP63 Recombinant Protein (N-His)
Brand: abinScience
SKU: HD664012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HD664012
Description	Recombinant Human CEP63 Protein, N-His (HD664012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Expression system	E. coli
Accession	Q96MT8
Protein length	Met1-Ile309
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	CEP63, Centrosomal protein of 63 kDa, Cep63
Background	Centrosomal protein of 63 kDa is a ~81 kDa protein. Required for normal spindle assembly. Plays a key role in mother-centriole-dependent centriole duplication; the function seems also to involve CEP152, CDK5RAP2 and WDR62 through a stepwise assembled complex at the centrosome that recruits CDK2 required for centriole duplication. Reported to be required for centrosomal recruitment of CEP152; however, this function has been questioned. Also recruits CDK1 to centrosomes. Plays a role in DNA damage response. 1. Löffler, H. et al. (2011) Cancer research 71, 2129-39. PMID: 21406398 2. Sir, JH. et al. (2011) Nature genetics 43, 1147-53. PMID: 21983783 3. Kodani, A. et al. (2015) eLife 4. PMID: 26297806 4. Kodani, A. et al. (2022) EMBO reports 23, e52211. PMID: 35793002 5. Ling, H. et al. (2022) Oncogene 41, 4433-4445. PMID: 35989368
Note	For research use only

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Datasheet

Human CEP63 Recombinant Protein (N-His).pdf

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Human CEP63 Recombinant Protein (N-His) (HD664012)

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