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| カタログ番号 | HC562013 | ||||
|---|---|---|---|---|---|
| 種反応性 | Human | ||||
| アプリケーション | ELISA, IF, IP | ||||
| 宿主種 | Mouse | ||||
| クローン性 | Monoclonal | ||||
| アイソタイプ | IgG2a | ||||
| クローンID | SAA0262 | ||||
| ターゲット | CHD4, Mi2-beta, Chromodomain-helicase-DNA-binding protein 4, CHD-4, Mi-2 autoantigen 218 kDa protein, ATP-dependent helicase CHD4 | ||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||
| 純度 | >95% as determined by SDS-PAGE. | ||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||
| アクセッション番号 | Q14839 | ||||
| RRID | Anti-Human CHD4 IP Antibody (SAA0262) (abinScience Cat# HC562013, RRID:AB_3729796) |
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| 形態 | Liquid | ||||
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 背景 | ATP-dependent chromatin remodeler CHD4 is a ~218 kDa protein. ATP-dependent chromatin-remodeling factor that binds and distorts nucleosomal DNA. Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin. Localizes to acetylated damaged chromatin in a ZMYND8-dependent manner, to promote transcriptional repression and double-strand break repair by homologous recombination. Involved in neurogenesis. 1. Hoffmeister, H. et al. (2017) Nucleic acids research 45, 10534-10554. PMID: 28977666 2. Farnung, L. et al. (2020) eLife 9. PMID: 32543371 3. Le Guezennec, X. et al. (2006) Molecular and cellular biology 26, 843-51. PMID: 16428440 4. Sillibourne, JE. et al. (2007) Molecular biology of the cell 18, 3667-80. PMID: 17626165 5. Tong, JK. et al. (1998) Nature 395, 917-21. PMID: 9804427 6. Gong, F. et al. (2015) Genes & development 29, 197-211. PMID: 25593309 | ||||
| 注意事項 | For research use only. |
SDS-PAGE for Anti-Human CHD4 IP Antibody (SAA0262)
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中国武漢市深敦寺路666号C棟、武漢、430206
