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| カタログ番号 | HF508013 | ||||
|---|---|---|---|---|---|
| 種反応性 | Human | ||||
| アプリケーション | ELISA, IF, IP | ||||
| 宿主種 | Mouse | ||||
| クローン性 | Monoclonal | ||||
| アイソタイプ | IgG2a | ||||
| クローンID | SAA0198 | ||||
| ターゲット | WD repeat-containing protein 39, Probable cytosolic iron-sulfur protein assembly protein CIAO1, WDR39, CIA1, CIAO1 | ||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||
| 純度 | >95% as determined by SDS-PAGE. | ||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||
| アクセッション番号 | O76071 | ||||
| RRID | Anti-Human CIAO1 IP Antibody (SAA0198) (abinScience Cat# HF508013, RRID:AB_3729732) |
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| 形態 | Liquid | ||||
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 背景 | Probable cytosolic iron-sulfur protein assembly protein CIAO1 is a ~37 kDa protein. Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. As a CIA complex component, interacts specifically with CIAO2A or CIAO2B and MMS19 to assist different branches of iron-sulfur protein assembly, depending of its interactors. The complex CIAO1:CIAO2B:MMS19 binds to and facilitates the assembly of most cytosolic-nuclear Fe/S proteins. CIAO1:CIAO2A specifically matures ACO1 and stabilizes IREB2. Seems to specifically modulate the transactivation activity of WT1. 1. Srinivasan, V. et al. (2007) Structure (London, England : 1993) 15, 1246-57. PMID: 17937914 2. Stehling, O. et al. (2013) Cell metabolism 18, 187-98. PMID: 23891004 3. Maio, N. et al. (2024) The Journal of clinical investigation 134. PMID: 38950322 4. Johnstone, RW. et al. (1998) The Journal of biological chemistry 273, 10880-7. PMID: 9556563 5. Ito, S. et al. (2010) Molecular cell 39, 632-40. PMID: 20797633 | ||||
| 注意事項 | For research use only. |
SDS-PAGE for Anti-Human CIAO1 IP Antibody (SAA0198)
+86-027-65523339
中国武漢市深敦寺路666号C棟、武漢、430206
