

| Numéro de catalogue | HF643014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human CP Polyclonal Antibody (HF643014) is a rabbit polyclonal antibody detecting Ceruloplasmin; 1.16.3.1; Ferroxidase; CP. Suitable for Human.
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human CP (Asp789-Gly1065). | ||||||||
| Cible | Ceruloplasmin; 1.16.3.1; Ferroxidase; CP | ||||||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | P00450 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Contexte | Ceruloplasmin (CP) is a ~122 kDa protein. Multifunctional blue, copper-binding (6-7 atoms per molecule) glycoprotein. It has ferroxidase activity oxidizing Fe(2+) to Fe(3+) without releasing radical oxygen species. It is involved in iron transport across the cell membrane. Copper ions provide a large number of enzymatic activites. Oxidizes highly toxic ferrous ions to the ferric state for further incorporation onto apo-transferrins, catalyzes Cu(+) oxidation and promotes the oxidation of biogenic amines such as norepinephrin and serotonin. 1. Hochstrasser, H. et al. (2005) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 19, 1851-3. PMID: 16150804 2. Stoj, C. et al. (2003) FEBS letters 554, 422-6. PMID: 14623105 3. Young, SN. et al. (1972) The Biochemical journal 129, 273-83. PMID: 4643313 4. Osaki, S. et al. (1966) The Journal of biological chemistry 241, 2746-51. PMID: 5912351 5. Park, YS. et al. (1999) FEBS letters 458, 133-6. PMID: 10481051 6. Shiva, S. et al. (2006) Nature chemical biology 2, 486-93. PMID: 16906150 | ||||||||
| Note | For research use only |
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