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Anti-Human Cathepsin B Monoclonal Antibody (1A489) (HY436015)

Anti-Human Cathepsin B Monoclonal Antibody (1A489)
Anti-Human Cathepsin B Monoclonal Antibody (1A489)
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Aperçu
Numéro de catalogueHY436015
Description
Anti-Human CTSB Monoclonal Antibody (1A489) [1A489] (HY436015) is a mouse monoclonal antibody detecting CTSB in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Recombinant — Superior batch-to-batch reproducibility with defined sequences.
  • ●Multi-Application — Validated across multiple applications.
Reactivité des espècesHuman
ApplicationsELISA, IHC, WB
Espèce hôteMouse
ClonalitéMonoclonal
IsotypeIgG
ID de clone1A489
Immunogène E. coli - derived recombinant human CTSB (Leu80-Asp333).
Cible Cathepsin B, EC:3.4.22.1, APP secretase, APPS, Cathepsin B1, Cathepsin B light chain, Cathepsin B heavy chain, CTSB
Niveau d'endotoxines < 10 EU/mg
Pureté >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès P07858
Forme Liquid
Tampon de stockage 0.01M PBS pH 7.4.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte

Cathepsin B (CTSB) is a ~37 kDa protein. Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Cleaves matrix extracellular phosphoglycoprotein MEPE. Involved in the solubilization of cross-linked TG/thyroglobulin in the thyroid follicle lumen. Has also been implicated in tumor invasion and metastasis.

1. Guo, R. et al. (2002) Biochemical and biophysical research communications 297, 38-45. PMID: 12220505
2. Ritonja, A. et al. (1985) FEBS letters 181, 169-72. PMID: 3972105
Note For research use only.
Images
  • Anti-Human Cathepsin B Monoclonal Antibody (1A489)

    SDS-PAGE

    SDS-PAGE for Anti-Human CTSB Monoclonal Antibody (1A489)

Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommandation

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