Anti-CTSB Polyclonal Antibody (HY436014)

Name: Anti-CTSB Polyclonal Antibody
Brand: abinScience
SKU: HY436014
Price: 168 USD
Availability: InStock

Datasheet Share product Copy info

Price(USD):

Spec:

50ug
100ug

Number:

Get quote

Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HY436014

Description

Anti-CTSB Polyclonal Antibody (HY436014) is a rabbit polyclonal antibody detecting CTSB in ELISA, IHC, WB. Suitable for Human, Bovine, Macaca fascicularis, Ovis aries, and Pongo abelii.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human CTSB (Leu80-Asp333).

Target

APP secretase, CPSB, Cathepsin B, Cathepsin B1, CTSB, APPS

Purification

Purified by antigen affinity column.

Accession

P07858

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Cathepsin B (CTSB) is a ~37 kDa protein. Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Cleaves matrix extracellular phosphoglycoprotein MEPE. Involved in the solubilization of cross-linked TG/thyroglobulin in the thyroid follicle lumen. Has also been implicated in tumor invasion and metastasis.

1. Guo, R. et al. (2002) Biochemical and biophysical research communications 297, 38-45. PMID: 12220505

2. Ritonja, A. et al. (1985) FEBS letters 181, 169-72. PMID: 3972105

Note

For research use only.

Images