Anti-Human CTSB Monoclonal Antibody (1A489) (HY436015)

Name: Anti-Human CTSB Monoclonal Antibody (1A489)
Brand: abinScience
SKU: HY436015
Price: 106 USD
Availability: InStock

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Overview

Catalog No.	HY436015
Description	Anti-Human CTSB Monoclonal Antibody (1A489) [1A489] (HY436015) is a mouse monoclonal antibody detecting CTSB in ELISA, IHC, WB. Suitable for Human. Highlights ●Recombinant — Superior batch-to-batch reproducibility with defined sequences. ●Multi-Application — Validated across multiple applications.
Species reactivity	Human
Applications	ELISA, IHC, WB
Host species	Mouse
Isotype	IgG
Clone ID	1A489
Clonality	Monoclonal
Immunogen	E. coli - derived recombinant human CTSB (Leu80-Asp333).
Target	Cathepsin B, EC:3.4.22.1, APP secretase, APPS, Cathepsin B1, Cathepsin B light chain, Cathepsin B heavy chain, CTSB
Purification	Protein A/G purified from cell culture supernatant.
Accession	P07858
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background	Cathepsin B (CTSB) is a ~37 kDa protein. Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Cleaves matrix extracellular phosphoglycoprotein MEPE. Involved in the solubilization of cross-linked TG/thyroglobulin in the thyroid follicle lumen. Has also been implicated in tumor invasion and metastasis. 1. Guo, R. et al. (2002) Biochemical and biophysical research communications 297, 38-45. PMID: 12220505 2. Ritonja, A. et al. (1985) FEBS letters 181, 169-72. PMID: 3972105
Note	For research use only.