Anti-Human CX3CL1/Fractalkine Recombinant Antibody (SAA0469), FITC (HX143117)

Name: Anti-Human CX3CL1/Fractalkine Recombinant Antibody (SAA0469), FITC
Brand: abinScience
SKU: HX143117
Price: 196 USD
Availability: InStock

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Número de catálogo	HX143117
Reactividad de especies	Human
Aplicaciones	ELISA, FCM
Especie huésped	Mouse
Clonalidad	Monoclonal
Isotipo	IgG2a, kappa
ID de clon	SAA0469
Conjugación	FITC
Objetivo	Small-inducible cytokine D1, Fractalkine, Neurotactin, C-X3-C motif chemokine 1, NTT, CX3CL1, SCYD1, FKN, CX3C membrane-anchored chemokine
Nivel de endotoxinas	Please contact with the lab for this information.
Productos asociados	Mouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173), FITC
Número de acceso	P78423
Forma	Liquid
Buffer de almacenamiento	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Store at 4°C for 12 months. Protect from light. Do not freeze.
Fondo	Fractalkine (CX3CL1) is a ~42 kDa protein. Chemokine that acts as a ligand for both CX3CR1 and integrins ITGAV:ITGB3 and ITGA4:ITGB1. The CX3CR1-CX3CL1 signaling exerts distinct functions in different tissue compartments, such as immune response, inflammation, cell adhesion and chemotaxis. Regulates leukocyte adhesion and migration processes at the endothelium. Can activate integrins in both a CX3CR1-dependent and CX3CR1-independent manner. In the presence of CX3CR1, activates integrins by binding to the classical ligand-binding site (site 1) in integrins. 1. Nishimura, M. et al. (2002) Journal of immunology (Baltimore, Md. : 1950) 168, 6173-80. PMID: 12055230 2. Xue, X. et al. (2011) PLoS pathogens 7, e1002162. PMID: 21829356 3. Fujita, M. et al. (2012) Journal of immunology (Baltimore, Md. : 1950) 189, 5809-19. PMID: 23125415 4. Fong, AM. et al. (1998) The Journal of experimental medicine 188, 1413-9. PMID: 9782118 5. Mizoue, LS. et al. (1999) Biochemistry 38, 1402-14. PMID: 9931005 6. Bazan, JF. et al. (1997) Nature 385, 640-4. PMID: 9024663 7. Pan, Y. et al. (1997) Nature 387, 611-7. PMID: 9177350 8. Fujita, M. et al. (2014) PloS one 9, e96372. PMID: 24789099
Nota	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Anti-Human CX3CL1/Fractalkine Recombinant Antibody (SAA0469), FITC.pdf

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