Anti-Human CX3CL1/Fractalkine Recombinant Antibody (SAA0469), FITC (HX143117)

Name: Anti-Human CX3CL1/Fractalkine Recombinant Antibody (SAA0469), FITC
Brand: abinScience
SKU: HX143117
Price: 196 USD
Availability: InStock

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Numéro de catalogue	HX143117
Reactivité des espèces	Human
Applications	ELISA, FCM
Espèce hôte	Mouse
Clonalité	Monoclonal
Isotype	IgG2a, kappa
ID de clone	SAA0469
Conjugaison	FITC
Cible	Small-inducible cytokine D1, Fractalkine, Neurotactin, C-X3-C motif chemokine 1, NTT, CX3CL1, SCYD1, FKN, CX3C membrane-anchored chemokine
Niveau d'endotoxines	Please contact with the lab for this information.
Produits associés	Mouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173), FITC
Numéro d'accès	P78423
Forme	Liquid
Tampon de stockage	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Contexte	Fractalkine (CX3CL1) is a ~42 kDa protein. Chemokine that acts as a ligand for both CX3CR1 and integrins ITGAV:ITGB3 and ITGA4:ITGB1. The CX3CR1-CX3CL1 signaling exerts distinct functions in different tissue compartments, such as immune response, inflammation, cell adhesion and chemotaxis. Regulates leukocyte adhesion and migration processes at the endothelium. Can activate integrins in both a CX3CR1-dependent and CX3CR1-independent manner. In the presence of CX3CR1, activates integrins by binding to the classical ligand-binding site (site 1) in integrins. 1. Nishimura, M. et al. (2002) Journal of immunology (Baltimore, Md. : 1950) 168, 6173-80. PMID: 12055230 2. Xue, X. et al. (2011) PLoS pathogens 7, e1002162. PMID: 21829356 3. Fujita, M. et al. (2012) Journal of immunology (Baltimore, Md. : 1950) 189, 5809-19. PMID: 23125415 4. Fong, AM. et al. (1998) The Journal of experimental medicine 188, 1413-9. PMID: 9782118 5. Mizoue, LS. et al. (1999) Biochemistry 38, 1402-14. PMID: 9931005 6. Bazan, JF. et al. (1997) Nature 385, 640-4. PMID: 9024663 7. Pan, Y. et al. (1997) Nature 387, 611-7. PMID: 9177350 8. Fujita, M. et al. (2014) PloS one 9, e96372. PMID: 24789099
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Anti-Human CX3CL1/Fractalkine Recombinant Antibody (SAA0469), FITC.pdf

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