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Anti-Human CX3CL1/Fractalkine Recombinant Antibody (SAA0469) (HX143107)

Anti-Human CX3CL1/Fractalkine Recombinant Antibody (SAA0469)
Anti-Human CX3CL1/Fractalkine Recombinant Antibody (SAA0469)
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Especificación:
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  • 100ug
Número:
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  • SDS

Vista general
Número de catálogoHX143107
Reactividad de especiesHuman
AplicacionesELISA, FCM
Especie huéspedMouse
ClonalidadMonoclonal
IsotipoIgG2a, kappa
ID de clonSAA0469
Objetivo Small-inducible cytokine D1, Fractalkine, Neurotactin, C-X3-C motif chemokine 1, NTT, CX3CL1, SCYD1, FKN, CX3C membrane-anchored chemokine
Nivel de endotoxinas Please contact with the lab for this information.
Pureza >95% as determined by SDS-PAGE.
Purificación Protein A/G purified from cell culture supernatant.
Número de acceso P78423
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 0.09% Sodium azide.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Fondo

Fractalkine (CX3CL1) is a ~42 kDa protein. Chemokine that acts as a ligand for both CX3CR1 and integrins ITGAV:ITGB3 and ITGA4:ITGB1. The CX3CR1-CX3CL1 signaling exerts distinct functions in different tissue compartments, such as immune response, inflammation, cell adhesion and chemotaxis. Regulates leukocyte adhesion and migration processes at the endothelium. Can activate integrins in both a CX3CR1-dependent and CX3CR1-independent manner. In the presence of CX3CR1, activates integrins by binding to the classical ligand-binding site (site 1) in integrins.

1. Nishimura, M. et al. (2002) Journal of immunology (Baltimore, Md. : 1950) 168, 6173-80. PMID: 12055230
2. Xue, X. et al. (2011) PLoS pathogens 7, e1002162. PMID: 21829356
3. Fujita, M. et al. (2012) Journal of immunology (Baltimore, Md. : 1950) 189, 5809-19. PMID: 23125415
4. Fong, AM. et al. (1998) The Journal of experimental medicine 188, 1413-9. PMID: 9782118
5. Mizoue, LS. et al. (1999) Biochemistry 38, 1402-14. PMID: 9931005
6. Bazan, JF. et al. (1997) Nature 385, 640-4. PMID: 9024663
7. Pan, Y. et al. (1997) Nature 387, 611-7. PMID: 9177350
8. Fujita, M. et al. (2014) PloS one 9, e96372. PMID: 24789099
Nota For research use only.
Imágenes
  • Anti-Human CX3CL1/Fractalkine Recombinant Antibody (SAA0469)

    SDS-PAGE

    SDS-PAGE for Anti-Human CX3CL1/Fractalkine Antibody (SAA0469)

Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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