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Anti-Human CX3CL1/Fractalkine Recombinant Antibody (SAA0469) (HX143107)

Anti-Human CX3CL1/Fractalkine Recombinant Antibody (SAA0469)
Anti-Human CX3CL1/Fractalkine Recombinant Antibody (SAA0469)
Цена(USD):
Спецификация:
  • 50ug
  • 100ug
Количество:
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  • Даташит

  • SDS

Обзор
Каталожный номерHX143107
Реактивность видовHuman
ПримененияELISA, FCM
Хозяинский видMouse
КлоональностьMonoclonal
ИзотипIgG2a, kappa
ID клонаSAA0469
Цель Small-inducible cytokine D1, Fractalkine, Neurotactin, C-X3-C motif chemokine 1, NTT, CX3CL1, SCYD1, FKN, CX3C membrane-anchored chemokine
Уровень эндотоксинов Please contact with the lab for this information.
Чистота >95% as determined by SDS-PAGE.
Очистка Protein A/G purified from cell culture supernatant.
Номер доступа P78423
Форма Liquid
Буфер хранения 0.01M PBS, pH 7.4, 0.09% Sodium azide.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Устойчивость и хранение Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Фон

Fractalkine (CX3CL1) is a ~42 kDa protein. Chemokine that acts as a ligand for both CX3CR1 and integrins ITGAV:ITGB3 and ITGA4:ITGB1. The CX3CR1-CX3CL1 signaling exerts distinct functions in different tissue compartments, such as immune response, inflammation, cell adhesion and chemotaxis. Regulates leukocyte adhesion and migration processes at the endothelium. Can activate integrins in both a CX3CR1-dependent and CX3CR1-independent manner. In the presence of CX3CR1, activates integrins by binding to the classical ligand-binding site (site 1) in integrins.

1. Nishimura, M. et al. (2002) Journal of immunology (Baltimore, Md. : 1950) 168, 6173-80. PMID: 12055230
2. Xue, X. et al. (2011) PLoS pathogens 7, e1002162. PMID: 21829356
3. Fujita, M. et al. (2012) Journal of immunology (Baltimore, Md. : 1950) 189, 5809-19. PMID: 23125415
4. Fong, AM. et al. (1998) The Journal of experimental medicine 188, 1413-9. PMID: 9782118
5. Mizoue, LS. et al. (1999) Biochemistry 38, 1402-14. PMID: 9931005
6. Bazan, JF. et al. (1997) Nature 385, 640-4. PMID: 9024663
7. Pan, Y. et al. (1997) Nature 387, 611-7. PMID: 9177350
8. Fujita, M. et al. (2014) PloS one 9, e96372. PMID: 24789099
Примечание For research use only.
Изображения
  • Anti-Human CX3CL1/Fractalkine Recombinant Antibody (SAA0469)

    SDS-PAGE

    SDS-PAGE for Anti-Human CX3CL1/Fractalkine Antibody (SAA0469)

Ссылки
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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