

| Numéro de catalogue | HT416015 |
|---|---|
| Description |
Anti-Human DCX Monoclonal Antibody (1A537) [1A537] (HT416015) is a mouse monoclonal antibody detecting DCX in ELISA, IHC, WB. Suitable for Human.
Highlights
|
| Reactivité des espèces | Human |
| Applications | ELISA, IHC, WB |
| Espèce hôte | Mouse |
| Clonalité | Monoclonal |
| Isotype | IgG |
| ID de clone | 1A537 |
| Immunogène | E. coli - derived recombinant human DCX (Arg178-Gly276). |
| Cible | Neuronal migration protein doublecortin, Doublin, Lissencephalin-X, Lis-X, DCX |
| Niveau d'endotoxines | < 10 EU/mg |
| Pureté | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Numéro d'accès | O43602 |
| Forme | Liquid |
| Tampon de stockage | 0.01M PBS pH 7.4. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Contexte | Neuronal migration protein doublecortin (DCX) is a ~40 kDa protein. Microtubule-associated protein required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCLK1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May be part with PAFAH1B1/LIS-1 of overlapping, but distinct, signaling pathways that promote neuronal migration. |
| Note | For research use only. |

SDS-PAGE for Anti-Human DCX Monoclonal Antibody (1A537)




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