

| Catalog No. | HT416014 | ||||||
|---|---|---|---|---|---|---|---|
| Species reactivity | Human, Mouse, Rat | ||||||
| Applications | ELISA, IHC, WB | ||||||
| Host species | Rabbit | ||||||
| Isotype | IgG | ||||||
| Clonality | Polyclonal | ||||||
| Immunogen | E. coli - derived recombinant Human DCX (Arg178-Gly276). | ||||||
| Target | Lis-X, LISX, DCX, Neuronal migration protein doublecortin, Doublin, Lissencephalin-X, DBCN | ||||||
| Endotoxin level | Please contact with the lab for this information. | ||||||
| Purification | Purified by antigen affinity column. | ||||||
| Accession | O43602 | ||||||
| Form | Liquid | ||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
||||||
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. | ||||||
| Shipping | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. | ||||||
| Product Usage Information |
| ||||||
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||
| Background | Neuronal migration protein doublecortin (DCX) is a ~40 kDa protein. Microtubule-associated protein required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCLK1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May be part with PAFAH1B1/LIS-1 of overlapping, but distinct, signaling pathways that promote neuronal migration. | ||||||
| Note | For research use only. |

Western blot analysis was performed using anti-Human DCX polyclonal antibody at 1ug/mL on recombinant Human DCX (Catalog No. HT416012).




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