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| カタログ番号 | HP866014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human DDA1 Polyclonal Antibody (HP866014) is a rabbit polyclonal antibody detecting DDA1 in ELISA, IHC, WB. Suitable for Human, Mouse.
Highlights
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| 種反応性 | Human, Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human DDA1 (Ala2-Thr102). | ||||||||
| ターゲット | Placenta cross-immune reaction antigen 1, PCIA1, PCIA-1, C19orf58, DDA1, DET1- and DDB1-associated protein 1 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q9BW61 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | DET1- and DDB1-associated protein 1 (DDA1) is a ~11 kDa protein. Functions as a component of numerous distinct DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. In the DCX complexes, acts as a scaffolding subunit required to stabilize the complex. 1. Pick, E. et al. (2007) Molecular and cellular biology 27, 4708-19. PMID: 17452440 2. Han, T. et al. (2017) Science (New York, N.Y.) 356. PMID: 28302793 3. Uehara, T. et al. (2017) Nature chemical biology 13, 675-680. PMID: 28437394 4. Faust, TB. et al. (2020) Nature chemical biology 16, 7-14. PMID: 31686031 5. Bussiere, DE. et al. (2020) Nature chemical biology 16, 15-23. PMID: 31819272 | ||||||||
| 注意事項 | For research use only. |
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