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| カタログ番号 | HY134014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human DEFA4 Polyclonal Antibody (HY134014) is a rabbit polyclonal antibody detecting DEFA4. Suitable for Human.
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human DEFA4 (Gly20-Asp97). | ||||||||
| ターゲット | Corticostatin HP-4, DEF4, DEFA4, Defensin alpha 4, HNP-4, HP-4, Neutrophil defensin 4 | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P12838 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 背景 | Defensin alpha 4 (DEFA4) is a ~10 kDa protein. Host-defense peptide that has antimicrobial activity against Gram-negative bacteria, and to a lesser extent also against Gram-positive bacteria and fungi. Exhibits antimicrobial activity against Gram-negative E.coli and E.aerogenes and Gram-positive S.faecalis, S.aureus and B.cereus and the yeast C.albicans (in vitro). Interacts with pathogenic surface proteins and toxins, such as HIV-1 surface protein gp120 and B.anthracis anthrax lethal factor lef. Protects blood cells against infection with HIV-1 (in vitro). Inhibits enzymatic activity of B.anthracis lef/anthrax lethal factor (in vitro). 1. Wu, Z. et al. (2004) The journal of peptide research : official journal of the American Peptide Society 64, 118-25. PMID: 15317502 2. Ericksen, B. et al. (2005) Antimicrobial agents and chemotherapy 49, 269-75. PMID: 15616305 3. Wilde, CG. et al. (1989) The Journal of biological chemistry 264, 11200-3. PMID: 2500436 4. Gabay, JE. et al. (1989) Proceedings of the National Academy of Sciences of the United States of America 86, 5610-4. PMID: 2501794 5. Hu, H. et al. (2019) Biochimica et biophysica acta. Biomembranes 1861, 835-844. PMID: 30658057 6. Szyk, A. et al. (2006) Protein science : a publication of the Protein Society 15, 2749-60. PMID: 17088326 | ||||||||
| 注意事項 | For research use only |
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