Anti-Human DLL4 Recombinant Antibody (21H3) (HV571013)

Name: Anti-Human DLL4 Recombinant Antibody (21H3)
Brand: abinScience
SKU: HV571013
Price: 126 USD
Availability: InStock

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20ug
50ug
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1mg

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Aperçu
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Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HV571013

Reactivité des espèces

Human

Applications

Blocking, ELISA, FCM

Espèce hôte

Mouse

Clonalité

Monoclonal

Isotype

IgG1-Kappa

ID de clone

21H3

Cible

Delta-like protein 4, Drosophila Delta homolog 4, Delta4, DLL4

Niveau d'endotoxines

Please contact with the lab for this information.

Pureté

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

Q9NR61

RRID

Anti-Human DLL4 Antibody (21H3) (abinScience Cat# HV571013, RRID:AB_3725371)

Forme

Liquid

Tampon de stockage

0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:2000-1:20000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Contexte

Delta-like protein 4 (DLL4) is a ~74 kDa protein. Involved in the Notch signaling pathway as Notch ligand. Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types.

1. Yoneya, T. et al. (2001) Journal of biochemistry 129, 27-34. PMID: 11134954

2. Brütsch, R. et al. (2010) Circulation research 107, 592-601. PMID: 20616313

3. Del Barrio, MG. et al. (2007) Development (Cambridge, England) 134, 3427-36. PMID: 17728344

Note

For research use only.

Isotype Control

Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21) (MV080207)

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