

| Numéro de catalogue | HD555014 | ||||||||
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| Description |
Anti-Human DNMBP Polyclonal Antibody (HD555014) is a rabbit polyclonal antibody detecting DNMBP. Suitable for Human.
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human DNMBP (Met1-Leu202). | ||||||||
| Cible | ARHGEF36, DNMBP, Dynamin-binding protein, KIAA1010, Scaffold protein Tuba, TUBA | ||||||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q6XZF7 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Contexte | Dynamin-binding protein (DNMBP) is a ~177 kDa protein. Plays a critical role as a guanine nucleotide exchange factor (GEF) for CDC42 in several intracellular processes associated with the actin and microtubule cytoskeleton. Regulates the structure of apical junctions through F-actin organization in epithelial cells. Participates in the normal lumenogenesis of epithelial cell cysts by regulating spindle orientation. Plays a role in ciliogenesis. May play a role in membrane trafficking between the cell surface and the Golgi. 1. Otani, T. et al. (2006) The Journal of cell biology 175, 135-46. PMID: 17015620 2. Rajabian, T. et al. (2009) Nature cell biology 11, 1212-8. PMID: 19767742 3. Qin, Y. et al. (2010) The Journal of cell biology 189, 661-9. PMID: 20479467 | ||||||||
| Note | For research use only |
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