

| Catalog No. | HD555012 |
|---|---|
| Description |
Recombinant Human DNMBP Protein, N-His (HD555012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| Expression system | E. coli |
| Accession | Q6XZF7 |
| Protein length | Met1-Leu202 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Species | Homo sapiens (Human) |
| Nature | Recombinant |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >90% as determined by SDS-PAGE. |
| Form | Lyophilized |
| Storage buffer | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Shipping | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternate Names | ARHGEF36, DNMBP, Dynamin-binding protein, KIAA1010, Scaffold protein Tuba, TUBA |
| Background | Dynamin-binding protein is a ~177 kDa protein. Plays a critical role as a guanine nucleotide exchange factor (GEF) for CDC42 in several intracellular processes associated with the actin and microtubule cytoskeleton. Regulates the structure of apical junctions through F-actin organization in epithelial cells. Participates in the normal lumenogenesis of epithelial cell cysts by regulating spindle orientation. Plays a role in ciliogenesis. May play a role in membrane trafficking between the cell surface and the Golgi. 1. Otani, T. et al. (2006) The Journal of cell biology 175, 135-46. PMID: 17015620 2. Rajabian, T. et al. (2009) Nature cell biology 11, 1212-8. PMID: 19767742 3. Qin, Y. et al. (2010) The Journal of cell biology 189, 661-9. PMID: 20479467 |
| Note | For research use only |
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