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Anti-Human DNMBP Polyclonal Antibody (HD555014)

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Overview
Catalog No.HD555014
Description
Anti-Human DNMBP Polyclonal Antibody (HD555014) is a rabbit polyclonal antibody detecting DNMBP. Suitable for Human.
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human DNMBP (Met1-Leu202).
Target ARHGEF36, DNMBP, Dynamin-binding protein, KIAA1010, Scaffold protein Tuba, TUBA
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession Q6XZF7
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Dynamin-binding protein (DNMBP) is a ~177 kDa protein. Plays a critical role as a guanine nucleotide exchange factor (GEF) for CDC42 in several intracellular processes associated with the actin and microtubule cytoskeleton. Regulates the structure of apical junctions through F-actin organization in epithelial cells. Participates in the normal lumenogenesis of epithelial cell cysts by regulating spindle orientation. Plays a role in ciliogenesis. May play a role in membrane trafficking between the cell surface and the Golgi.

1. Otani, T. et al. (2006) The Journal of cell biology 175, 135-46. PMID: 17015620
2. Rajabian, T. et al. (2009) Nature cell biology 11, 1212-8. PMID: 19767742
3. Qin, Y. et al. (2010) The Journal of cell biology 189, 661-9. PMID: 20479467
Note For research use only
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Formula
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Anti-Human DNMBP Polyclonal Antibody

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