Anti-Human EPHA2 Recombinant Antibody (SAA0832), APC (HB738137)

Name: Anti-Human EPHA2 Recombinant Antibody (SAA0832), APC
Brand: abinScience
SKU: HB738137
Price: 290 USD
Availability: InStock

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Numéro de catalogue	HB738137
Reactivité des espèces	Human, Mouse
Applications	FCM
Espèce hôte	Mouse
Clonalité	Monoclonal
Isotype	IgG2a
ID de clone	SAA0832
Conjugaison	APC
Cible	Epithelial cell kinase, Tyrosine-protein kinase receptor ECK, EPHA2, Ephrin type-A receptor 2, ECK
Niveau d'endotoxines	Please contact with the lab for this information.
Produits associés	Mouse IgG2a Recombinant Isotype Control Antibody (C1.18.4), APC
Numéro d'accès	P29317
Forme	Liquid
Tampon de stockage	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Contexte	Ephrin type-A receptor 2 (EPHA2) is a ~108 kDa protein. Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Activated by the ligand ephrin-A1/EFNA1 regulates migration, integrin-mediated adhesion, proliferation and differentiation of cells. Regulates cell adhesion and differentiation through DSG1/desmoglein-1 and inhibition of the ERK1/ERK2 (MAPK3/MAPK1, respectively) signaling pathway. May also participate in UV radiation-induced apoptosis and have a ligand-independent stimulatory effect on chemotactic cell migration.
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.