Anti-Human FBXO45 Polyclonal Antibody (HY575014)

Name: Anti-Human FBXO45 Polyclonal Antibody
Brand: abinScience
SKU: HY575014
Price: 96 USD
Availability: InStock

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Каталожный номер

HY575014

Описание

Anti-Human FBXO45 Polyclonal Antibody (HY575014) is a rabbit polyclonal antibody detecting FBXO45 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Реактивность видов

Human, Mouse, Rat

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant Human FBXO45 (Ser41-Gly286).

Цель

F-box/SPRY domain-containing protein 1, F-box only protein 45, hFbxo45, FBXO45, FBX45

Очистка

Purified by antigen affinity column.

Номер доступа

P0C2W1

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

F-box/SPRY domain-containing protein 1 (FBXO45) is a ~30 kDa protein. Component of E3 ubiquitin ligase complex consisting of FBXO45, MYCBP2 and SKP1. Functions in substrate recognition but also plays an important role in assembly of the complex. Required for normal neuromuscular synaptogenesis, axon pathfinding and neuronal migration. Regulates neuron migration during brain development through interaction with N-cadherin/CDH2 after secretion via a non-classical mechanism. Plays a role in the regulation of neurotransmission at mature neurons.

1. Desbois, M. et al. (2018) The Journal of biological chemistry 293, 13897-13909. PMID: 29997255

2. Richter, KT. et al. (2020) Cell death and differentiation 27, 758-772. PMID: 31285543

3. Tsai, M. et al. (2022) The Journal of biological chemistry 298, 102698. PMID: 36379255

Примечание

For research use only.

Изображения

Western blot

Western blot analysis was performed using anti-FBXO45 polyclonal antibody at FBXO45 on various samples.
Lane 1: Mouse brain lysate

Ссылки

Даташит

Anti-Human FBXO45 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

Наборы для анализа

Anti-Human FBXO45 Polyclonal Antibody (HY575014)

Обзор

Изображения

Ссылки

Даташит

SDS