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| カタログ番号 | HY398137 |
|---|---|
| 種反応性 | Human |
| アプリケーション | ELISA, FCM |
| 宿主種 | Mouse |
| クローン性 | Monoclonal |
| アイソタイプ | IgG1, kappa |
| クローンID | SAA0437 |
| 抱合 | APC |
| ターゲット | bFGF, FGF2, Basic fibroblast growth factor, HBGF-2, FGFB, FGF-2, Heparin-binding growth factor 2, Fibroblast growth factor 2 |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 関連製品 | Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21), APC |
| アクセッション番号 | P09038 |
| 形態 | Liquid |
| 保存バッファー | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 安定性と保存 | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| 背景 | Fibroblast growth factor 2 (FGF2/bFGF) is a ~30 kDa protein. Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. 1. Ornitz, DM. et al. (1996) The Journal of biological chemistry 271, 15292-7. PMID: 8663044 2. Mori, S. et al. (2017) Bioscience reports 37. PMID: 28302677 3. Shimoyama, Y. et al. (1991) Japanese journal of cancer research : Gann 82, 1263-70. PMID: 1721615 4. Gautschi, P. et al. (1986) FEBS letters 204, 203-7. PMID: 3732516 5. Gimenez-Gallego, G. et al. (1986) Biochemical and biophysical research communications 135, 541-8. PMID: 3964259 6. Mori, S. et al. (2013) PloS one 8, e57927. PMID: 23469107 |
| 注意事項 | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |
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