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Anti-Human FGF basic/FGF2/bFGF Recombinant Antibody (SAA0437) (HY398107)

Anti-Human FGF basic/FGF2/bFGF Recombinant Antibody (SAA0437)
Anti-Human FGF basic/FGF2/bFGF Recombinant Antibody (SAA0437)
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Overview
Catalog No.HY398107
Species reactivityHuman
ApplicationsELISA, FCM
Host speciesMouse
IsotypeIgG1, kappa
Clone IDSAA0437
Clonality Monoclonal
Target bFGF, FGF2, Basic fibroblast growth factor, HBGF-2, FGFB, FGF-2, Heparin-binding growth factor 2, Fibroblast growth factor 2
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P09038
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 0.09% Sodium azide.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background

Fibroblast growth factor 2 (FGF2/bFGF) is a ~30 kDa protein. Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro.

1. Ornitz, DM. et al. (1996) The Journal of biological chemistry 271, 15292-7. PMID: 8663044
2. Mori, S. et al. (2017) Bioscience reports 37. PMID: 28302677
3. Shimoyama, Y. et al. (1991) Japanese journal of cancer research : Gann 82, 1263-70. PMID: 1721615
4. Gautschi, P. et al. (1986) FEBS letters 204, 203-7. PMID: 3732516
5. Gimenez-Gallego, G. et al. (1986) Biochemical and biophysical research communications 135, 541-8. PMID: 3964259
6. Mori, S. et al. (2013) PloS one 8, e57927. PMID: 23469107
Note For research use only.
Images
  • Anti-Human FGF basic/FGF2/bFGF Recombinant Antibody (SAA0437)

    Bioactivity

    Detects Human FGF2/bFGF in indirect ELISAs.

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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