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Anti-Human FGF-23 Recombinant Antibody (SAA0441) (HV625107)

Anti-Human FGF-23 Recombinant Antibody (SAA0441)
Anti-Human FGF-23 Recombinant Antibody (SAA0441)
Anti-Human FGF-23 Recombinant Antibody (SAA0441)
Anti-Human FGF-23 Recombinant Antibody (SAA0441)
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  • データシート

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概要
カタログ番号HV625107
種反応性Human
アプリケーションELISA, FCM
宿主種Mouse
クローン性Monoclonal
アイソタイプIgG2a, kappa
クローンIDSAA0441
ターゲット Phosphatonin, FGF-23, HYPF, FGF23, Fibroblast growth factor 23, Tumor-derived hypophosphatemia-inducing factor
エンドトキシンレベル Please contact with the lab for this information.
純度 >95% as determined by SDS-PAGE.
精製 Protein A/G purified from cell culture supernatant.
アクセッション番号 Q9GZV9
形態 Liquid
保存バッファー 0.01M PBS pH 7.4

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

安定性と保存 Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

Fibroblast growth factor 23 (FGF23) is a ~27 kDa protein. Regulator of phosphate homeostasis. Inhibits renal tubular phosphate transport by reducing SLC34A1 levels. Up-regulates EGR1 expression in the presence of KL. Acts directly on the parathyroid to decrease PTH secretion. Regulator of vitamin-D metabolism.

1. Unknown (2000) Nature genetics 26, 345-8. PMID: 11062477
2. Bowe, AE. et al. (2001) Biochemical and biophysical research communications 284, 977-81. PMID: 11409890
3. Shimada, T. et al. (2004) Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 19, 429-35. PMID: 15040831
4. Wang, H. et al. (2008) Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 23, 939-48. PMID: 18282132
注意事項 For research use only.
イメージ
  • Anti-Human FGF-23 Recombinant Antibody (SAA0441)

    Flow Cytometry

    Flow-cytometry using anti-human FGF23 antibody.FGF23 Transfected CHO cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human FGF23 antibody monoclonal antibody (Catalog # HV625107 ,Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-mouse antibody (Catalog # MF690414) and cells analysed on a NovoCyte Flow Cytometer.

  • Anti-Human FGF-23 Recombinant Antibody (SAA0441)

    Bioactivity

    Detects recombinant human FGF23(Catalog No: HV625011) in indirect ELISA

参考文献
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
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Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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