Anti-Human FGF-23 Reference Antibody (Burosumab, RUO) (HV625016)

Name: Anti-Human FGF-23 Reference Antibody (Burosumab, RUO)
Brand: abinScience
SKU: HV625016
Price: 176 USD
Availability: InStock

Datasheet Share product Copy info

Price(USD):

Spec:

100ug
1mg
5mg
10mg
25mg
50mg
100mg

Number:

Get quote

Overview
Images
References
Datasheet
SDS

Overview

Catalog No.	HV625016
Description	Burosumab (HV625016) is a research-grade recombinant antibody targeting Phosphatonin. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG1-kappa
Expression system	Mammalian cells
Clonality	Monoclonal
Target	Phosphatonin, FGF-23, HYPF, FGF23, Fibroblast growth factor 23, Tumor-derived hypophosphatemia-inducing factor
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q9GZV9
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	KRN-23, UX-023, 1610833-03-8, KRN23
Background	Fibroblast growth factor 23 (FGF23) is a ~27 kDa protein. Regulator of phosphate homeostasis. Inhibits renal tubular phosphate transport by reducing SLC34A1 levels. Up-regulates EGR1 expression in the presence of KL. Acts directly on the parathyroid to decrease PTH secretion. Regulator of vitamin-D metabolism. 1. Unknown (2000) Nature genetics 26, 345-8. PMID: 11062477 2. Bowe, AE. et al. (2001) Biochemical and biophysical research communications 284, 977-81. PMID: 11409890 3. Shimada, T. et al. (2004) Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 19, 429-35. PMID: 15040831 4. Wang, H. et al. (2008) Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 23, 939-48. PMID: 18282132
Note	For research use only. Not suitable for clinical or therapeutic use.

Images

Bioactivity

SEC-HPLC detection for Research Grade Burosumab.
SDS-PAGE

SDS-PAGE for Research Grade Burosumab.
Bioactivity

Detects recombinant human FGF23(Catalog No: HV625022) in indirect ELISA
Bioactivity

Detects recombinant human FGF23(Catalog No: HV625011) in indirect ELISA

References

Datasheet

Anti-Human FGF-23 Reference Antibody (Burosumab, RUO).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human FGF-23 Reference Antibody (Burosumab, RUO) (HV625016)

Overview

Images

References

Datasheet

SDS

Quick access

Contact Us