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Anti-Human FSCN1 Monoclonal Antibody (1A596) (HS760035)

Anti-Human FSCN1 Monoclonal Antibody (1A596)
Anti-Human FSCN1 Monoclonal Antibody (1A596)
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Aperçu
Numéro de catalogueHS760035
Description
Anti-Human FSCN1 Monoclonal Antibody (1A596) [1A596] (HS760035) is a mouse monoclonal antibody detecting FSCN1 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Recombinant — Superior batch-to-batch reproducibility with defined sequences.
  • ●Multi-Application — Validated across multiple applications.
Reactivité des espècesHuman
ApplicationsELISA, IHC, WB
Espèce hôteMouse
ClonalitéMonoclonal
IsotypeIgG
ID de clone1A596
Immunogène E. coli - derived recombinant human FSCN1 (Gln277-Gly396).
Cible Fascin, 55 kDa actin-bundling protein, Singed-like protein, p55, FSCN1
Niveau d'endotoxines Please contact with the lab for this information.
Pureté >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès Q16658
Forme Liquid
Tampon de stockage 0.01M PBS pH 7.4.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte

Fascin (FSCN1) is a ~54 kDa protein. Actin-binding protein that contains 2 major actin binding sites. Organizes filamentous actin into parallel bundles. Plays a role in the organization of actin filament bundles and the formation of microspikes, membrane ruffles, and stress fibers. Important for the formation of a diverse set of cell protrusions, such as filopodia, and for cell motility and migration. Mediates reorganization of the actin cytoskeleton and axon growth cone collapse in response to NGF.

1. Jansen, S. et al. (2011) The Journal of biological chemistry 286, 30087-96. PMID: 21685497
2. Yang, S. et al. (2013) The Journal of biological chemistry 288, 274-84. PMID: 23184945
3. Chen, L. et al. (2010) Nature 464, 1062-6. PMID: 20393565
4. Deinhardt, K. et al. (2011) Science signaling 4, ra82. PMID: 22155786
Note For research use only.
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  • Anti-Human FSCN1 Monoclonal Antibody (1A596)

    SDS-PAGE

    SDS-PAGE for Anti-Human FSCN1 Monoclonal Antibody (1A596)

Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommandation

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