Anti-Human Frizzled-1 Recombinant Antibody (SAA0167), FITC (HV162117)

Name: Anti-Human Frizzled-1 Recombinant Antibody (SAA0167), FITC
Brand: abinScience
SKU: HV162117
Price: 223 USD
Availability: InStock

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概要
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概要

カタログ番号	HV162117
種反応性	Human
アプリケーション	FCM
宿主種	Human
クローン性	Monoclonal
アイソタイプ	IgG2, lambda
クローンID	SAA0167
抱合	FITC
ターゲット	FzE1, Frizzled-1, hFz1, Fz-1, FZD1
エンドトキシンレベル	Please contact with the lab for this information.
関連製品	Human IgG2 Recombinant Isotype Control Antibody (HyHEL-10), FITC
アクセッション番号	Q9UP38
形態	Liquid
保存バッファー	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
安定性と保存	Store at 4°C for 12 months. Protect from light. Do not freeze.
背景	Frizzled-1 (FZD1) is a ~71 kDa protein. Receptor for Wnt proteins. Activated by WNT3A, WNT3, WNT1 and to a lesser extent WNT2, but apparently not by WNT4, WNT5A, WNT5B, WNT6, WNT7A or WNT7B. Contradictory results showing activation by WNT7B have been described for mouse. Functions in the canonical Wnt/beta-catenin signaling pathway. The canonical Wnt/beta-catenin signaling pathway leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. 1. Gazit, A. et al. (1999) Oncogene 18, 5959-66. PMID: 10557084
注意事項	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

イメージ

Flow CytoMetry

Flow-cytometry using FITC anti-human FZD1 antibody. THP-1 cells were stained with an irrelevant antibody (Blue Histogram) or an FITC anti-human FZD1 monoclonal antibody (Catalog: HV162117, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.

参考文献

データシート