Anti-Human FZD1 Recombinant Antibody (SAA0167) (HV162107)

Name: Anti-Human FZD1 Recombinant Antibody (SAA0167)
Brand: abinScience
SKU: HV162107
Price: 191 USD
Availability: InStock

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Overview

Catalog No.	HV162107
Species reactivity	Human
Applications	FCM
Host species	Human
Isotype	IgG2, lambda
Clone ID	SAA0167
Clonality	Monoclonal
Target	FzE1, Frizzled-1, hFz1, Fz-1, FZD1
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q9UP38
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background	Frizzled-1 (FZD1) is a ~71 kDa protein. Receptor for Wnt proteins. Activated by WNT3A, WNT3, WNT1 and to a lesser extent WNT2, but apparently not by WNT4, WNT5A, WNT5B, WNT6, WNT7A or WNT7B. Contradictory results showing activation by WNT7B have been described for mouse. Functions in the canonical Wnt/beta-catenin signaling pathway. The canonical Wnt/beta-catenin signaling pathway leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. 1. Gazit, A. et al. (1999) Oncogene 18, 5959-66. PMID: 10557084
Note	For research use only.