Anti-Human Frizzled-1 Recombinant Antibody (SAA0167) (HV162107)

Name: Anti-Human Frizzled-1 Recombinant Antibody (SAA0167)
Brand: abinScience
SKU: HV162107
Price: 191 USD
Availability: InStock

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概要

カタログ番号	HV162107
種反応性	Human
アプリケーション	FCM
宿主種	Human
クローン性	Monoclonal
アイソタイプ	IgG2, lambda
クローンID	SAA0167
ターゲット	FzE1, Frizzled-1, hFz1, Fz-1, FZD1
エンドトキシンレベル	Please contact with the lab for this information.
純度	>95% as determined by SDS-PAGE.
精製	Protein A/G purified from cell culture supernatant.
アクセッション番号	Q9UP38
形態	Liquid
保存バッファー	0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
安定性と保存	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景	Frizzled-1 (FZD1) is a ~71 kDa protein. Receptor for Wnt proteins. Activated by WNT3A, WNT3, WNT1 and to a lesser extent WNT2, but apparently not by WNT4, WNT5A, WNT5B, WNT6, WNT7A or WNT7B. Contradictory results showing activation by WNT7B have been described for mouse. Functions in the canonical Wnt/beta-catenin signaling pathway. The canonical Wnt/beta-catenin signaling pathway leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. 1. Gazit, A. et al. (1999) Oncogene 18, 5959-66. PMID: 10557084
注意事項	For research use only.