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Anti-Human GPIHBP1 Polyclonal Antibody (HP876014)

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Aperçu
Numéro de catalogueHP876014
Description
Anti-Human GPIHBP1 Polyclonal Antibody (HP876014) is a rabbit polyclonal antibody detecting GPIHBP1 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Reactivité des espècesHuman
ApplicationsELISA, IHC, WB
Espèce hôteRabbit
ClonalitéPolyclonal
IsotypeIgG
Immunogène E. coli - derived recombinant Human GPIHBP1 (Ser59-Gln132).
Cible GPIHBP1, Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1, GPI-anchored HDL-binding protein 1, HBP1, High density lipoprotein-binding protein 1, GPI-HBP1
Purification Purified by antigen affinity column.
Numéro d'accès Q8IV16
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte

Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 (GPIHBP1) is a ~19 kDa protein. Mediates the transport of lipoprotein lipase LPL from the basolateral to the apical surface of endothelial cells in capillaries. Anchors LPL on the surface of endothelial cells in the lumen of blood capillaries. Protects LPL against loss of activity, and against ANGPTL4-mediated unfolding. Thereby, plays an important role in lipolytic processing of chylomicrons by LPL, triglyceride metabolism and lipid homeostasis. Binds chylomicrons and phospholipid particles that contain APOA5.

1. Mysling, S. et al. (2016) eLife 5. PMID: 27929370
2. Kristensen, KK. et al. (2018) Proceedings of the National Academy of Sciences of the United States of America 115, E6020-E6029. PMID: 29899144
3. Beigneux, AP. et al. (2009) Arteriosclerosis, thrombosis, and vascular biology 29, 956-62. PMID: 19304573
4. Coca-Prieto, I. et al. (2011) Journal of internal medicine 270, 224-8. PMID: 21314738
5. Gin, P. et al. (2007) Biochimica et biophysica acta 1771, 1464-8. PMID: 17997385
Note For research use only.
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Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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