Human GPIHBP1 Recombinant Protein (N-His) (HP876032)

Name: Human GPIHBP1 Recombinant Protein (N-His)
Brand: abinScience
SKU: HP876032
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HP876032
Description	Recombinant Human GPIHBP1 Protein, N-His (HP876032) expressed in E. coli, spanning Ser59-Pro184. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	Q8IV16
Protein length	Ser59-Pro184
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	15.60 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	GPI-HBP1, GPI-anchored HDL-binding protein 1, GPIHBP1, Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1, HBP1, High density lipoprotein-binding protein 1
Background	Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 is a ~19 kDa protein. Mediates the transport of lipoprotein lipase LPL from the basolateral to the apical surface of endothelial cells in capillaries. Anchors LPL on the surface of endothelial cells in the lumen of blood capillaries. Protects LPL against loss of activity, and against ANGPTL4-mediated unfolding. Thereby, plays an important role in lipolytic processing of chylomicrons by LPL, triglyceride metabolism and lipid homeostasis. Binds chylomicrons and phospholipid particles that contain APOA5. 1. Mysling, S. et al. (2016) eLife 5. PMID: 27929370 2. Kristensen, KK. et al. (2018) Proceedings of the National Academy of Sciences of the United States of America 115, E6020-E6029. PMID: 29899144 3. Beigneux, AP. et al. (2009) Arteriosclerosis, thrombosis, and vascular biology 29, 956-62. PMID: 19304573 4. Coca-Prieto, I. et al. (2011) Journal of internal medicine 270, 224-8. PMID: 21314738 5. Gin, P. et al. (2007) Biochimica et biophysica acta 1771, 1464-8. PMID: 17997385
Note	For research use only

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Datasheet

Human GPIHBP1 Recombinant Protein (N-His).pdf

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Human GPIHBP1 Recombinant Protein (N-His) (HP876032)

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