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Anti-Human GPR37L1 Polyclonal Antibody (HD416014)

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Vista general
Número de catálogoHD416014
Descripción
Anti-Human GPR37L1 Polyclonal Antibody (HD416014) is a rabbit polyclonal antibody detecting GPR37L1. Suitable for Human.
Reactividad de especiesHuman
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human GPR37L1 (Ala26-Met134).
Objetivo ETBR-LP-2, ETBRLP2, Endothelin B receptor-like protein 2, G-protein coupled receptor 37-like 1, GPR37L1
Nivel de endotoxinas Please contact with the lab for this information.
Purificación Purified by antigen affinity column.
Número de acceso O60883
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Fondo

G-protein coupled receptor 37-like 1 (GPR37L1) is a ~52 kDa protein. G-protein coupled receptor. Has been shown to bind the neuroprotective and glioprotective factor prosaposin (PSAP), leading to endocytosis followed by an ERK phosphorylation cascade. However, other studies have shown that prosaposin does not increase activity. It has been suggested that GPR37L1 is a constitutively active receptor which signals through the guanine nucleotide-binding protein G(s) subunit alpha. Participates in the regulation of postnatal cerebellar development by modulating the Shh pathway.

1. Coleman, JL. et al. (2016) Science signaling 9, ra36. PMID: 27072655
2. Meyer, RC. et al. (2013) Proceedings of the National Academy of Sciences of the United States of America 110, 9529-34. PMID: 23690594
3. Giddens, MM. et al. (2017) Neurobiology of disease 106, 181-190. PMID: 28688853
Nota For research use only
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
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Concentration
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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