Human GPR37L1 Recombinant Protein (N-His-KSI) (HD416012)

Name: Human GPR37L1 Recombinant Protein (N-His-KSI)
Brand: abinScience
SKU: HD416012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HD416012
Description	Recombinant Human GPR37L1 Protein, N-His-KSI (HD416012) expressed in E. coli, spanning Ala26-Met134. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	O60883
Protein length	Ala26-Met134
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	27.68 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	ETBR-LP-2, ETBRLP2, Endothelin B receptor-like protein 2, G-protein coupled receptor 37-like 1, GPR37L1
Background	G-protein coupled receptor 37-like 1 is a ~52 kDa protein. G-protein coupled receptor. Has been shown to bind the neuroprotective and glioprotective factor prosaposin (PSAP), leading to endocytosis followed by an ERK phosphorylation cascade. However, other studies have shown that prosaposin does not increase activity. It has been suggested that GPR37L1 is a constitutively active receptor which signals through the guanine nucleotide-binding protein G(s) subunit alpha. Participates in the regulation of postnatal cerebellar development by modulating the Shh pathway. 1. Coleman, JL. et al. (2016) Science signaling 9, ra36. PMID: 27072655 2. Meyer, RC. et al. (2013) Proceedings of the National Academy of Sciences of the United States of America 110, 9529-34. PMID: 23690594 3. Giddens, MM. et al. (2017) Neurobiology of disease 106, 181-190. PMID: 28688853
Note	For research use only

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Datasheet

Human GPR37L1 Recombinant Protein (N-His-KSI).pdf

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Human GPR37L1 Recombinant Protein (N-His-KSI) (HD416012)

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