Anti-Human HCN4 Recombinant Antibody (N114/10.1) (HY088013)

Name: Anti-Human HCN4 Recombinant Antibody (N114/10.1)
Brand: abinScience
SKU: HY088013
Price: 126 USD
Availability: InStock

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Aperçu
Images
Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HY088013

Reactivité des espèces

Human

Applications

IF, IHC, WB

Espèce hôte

Mouse

Clonalité

Monoclonal

Isotype

IgG1

ID de clone

N114/10.1

Cible

HCN4, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4

Niveau d'endotoxines

Please contact with the lab for this information.

Pureté

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

Q9Y3Q4

Forme

Liquid

Tampon de stockage

0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Contexte

Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (HCN4) is a ~129 kDa protein. Hyperpolarization-activated ion channel that are permeable to Na(+) and K(+) ions with very slow activation and inactivation. Exhibits higher selectivity for K(+) over Na(+) ions. Contributes to the native pacemaker currents in heart (If) that regulate the rhythm of heart beat (Probable). Contributes to the native pacemaker currents in neurons (Ih) (Probable). May mediate responses to sour stimuli.

1. Ludwig, A. et al. (1999) The EMBO journal 18, 2323-9. PMID: 10228147

2. Seifert, R. et al. (1999) Proceedings of the National Academy of Sciences of the United States of America 96, 9391-6. PMID: 10430953

3. Xu, X. et al. (2010) The Journal of biological chemistry 285, 37082-91. PMID: 20829353

4. Milanesi, R. et al. (2006) The New England journal of medicine 354, 151-7. PMID: 16407510

5. Ueda, K. et al. (2009) Journal of human genetics 54, 115-21. PMID: 19165230

Note

For research use only.

Isotype Control

Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21) (MV080207)

Images

Bioactivity

SEC-HPLC detection for Anti-Human HCN4 Antibody (N114/10.1).
SDS-PAGE

SDS-PAGE for Anti-Human HCN4 Antibody (N114/10.1).

Reférences

Fiche technique

Anti-Human HCN4 Recombinant Antibody (N114/10.1).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

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