Anti-HCN4 Recombinant Nanobody (SAA2585) (HY088043)

Name: Anti-HCN4 Recombinant Nanobody (SAA2585)
Brand: abinScience
SKU: HY088043
Price: 191 USD
Availability: InStock

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References
Datasheet
SDS

Overview

Catalog No.

HY088043

Description

Anti-HCN4 Nanobody (SAA2585) [SAA2585] (HY088043) is a alpaca monoclonal antibody detecting HCN4 in ELISA. Suitable for Human, Mouse, and Rabbit.

Highlights

●Multi-Species — Cross-reactive for translational research.

Species reactivity

Rabbit

Applications

ELISA

Host species

Alpaca

Isotype

VHH-His

Clone ID

SAA2585

Clonality

Monoclonal

Target

HCN4, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Purified by Nickel column.

Accession

Q9Y3Q4

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (HCN4) is a ~129 kDa protein. Hyperpolarization-activated ion channel that are permeable to Na(+) and K(+) ions with very slow activation and inactivation. Exhibits higher selectivity for K(+) over Na(+) ions. Contributes to the native pacemaker currents in heart (If) that regulate the rhythm of heart beat (Probable). Contributes to the native pacemaker currents in neurons (Ih) (Probable). May mediate responses to sour stimuli.

1. Ludwig, A. et al. (1999) The EMBO journal 18, 2323-9. PMID: 10228147

2. Seifert, R. et al. (1999) Proceedings of the National Academy of Sciences of the United States of America 96, 9391-6. PMID: 10430953

3. Xu, X. et al. (2010) The Journal of biological chemistry 285, 37082-91. PMID: 20829353

4. Milanesi, R. et al. (2006) The New England journal of medicine 354, 151-7. PMID: 16407510

5. Ueda, K. et al. (2009) Journal of human genetics 54, 115-21. PMID: 19165230

Note

For research use only

Images

References

Datasheet

Anti-HCN4 Recombinant Nanobody (SAA2585).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-HCN4 Recombinant Nanobody (SAA2585) (HY088043)

Overview

Images

References

Datasheet

SDS

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