Anti-Human HCRTR2 Polyclonal Antibody (HD507014)

Name: Anti-Human HCRTR2 Polyclonal Antibody
Brand: abinScience
SKU: HD507014
Price: 168 USD
Availability: InStock

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Especificación:

50ug
100ug

Número:

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Número de catálogo

HD507014

Descripción

Anti-Human HCRTR2 Polyclonal Antibody (HD507014) is a rabbit polyclonal antibody detecting HCRTR2. Suitable for Human.

Reactividad de especies

Human, Mouse, Rat

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant Human HCRTR2 (Ser2-Glu54&Glu192-Met222&Leu367-Trp444).

Objetivo

HCRTR2, Hypocretin receptor type 2, ORXR2, OX2R, OXR2, Orexin receptor type 2, Ox-2-R, Ox2-R, Ox2R

Nivel de endotoxinas

Please contact with the lab for this information.

Purificación

Purified by antigen affinity column.

Número de acceso

O43614

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Fondo

Orexin receptor type 2 (HCRTR2) is a ~50 kDa protein. G-protein coupled receptor that binds neuropeptides orexin-A and orexin-B, two neuropeptides derived from a common precursor, prepro-orexin. Upon neuropeptide ligand binding, HCRTR2 can couple with both G(q)/11 and G(i)/o heterotrimeric G-proteins thereby initiating distinct downstream signaling cascades. Involved in regulating the sleep-wake cycle. Contributes to central regulation of glucose homeostasis.

1. Yin, J. et al. (2016) Nature structural & molecular biology 23, 293-9. PMID: 26950369

2. Hong, C. et al. (2021) Nature communications 12, 815. PMID: 33547286

3. Yin, J. et al. (2022) Nature communications 13, 2902. PMID: 35614071

4. Sakurai, T. et al. (1998) Cell 92, 573-85. PMID: 9491897

Nota

For research use only

Imágenes

Referencias

Datasheet

Anti-Human HCRTR2 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo

Anti-Human HCRTR2 Polyclonal Antibody (HD507014)

Vista general

Imágenes

Referencias

Datasheet

SDS