Anti-Human HSP90B1/GRP94 Recombinant Antibody (SAA1937) (HB250013)

Name: Anti-Human HSP90B1/GRP94 Recombinant Antibody (SAA1937)
Brand: abinScience
SKU: HB250013
Price: 196 USD
Availability: InStock

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50ug
100ug
1mg

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Aperçu
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Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HB250013

Reactivité des espèces

Human

Applications

ELISA

Espèce hôte

Mouse

Clonalité

Monoclonal

Isotype

IgG2a, kappa

ID de clone

SAA1937

Cible

94 kDa glucose-regulated protein, HSP90B1, gp96 homolog, GRP94, Heat shock protein 90 kDa beta member 1, Endoplasmin, TRA1, Tumor rejection antigen 1, GRP-94

Niveau d'endotoxines

Please contact with the lab for this information.

Pureté

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

P14625

RRID

Anti-Human HSP90B1/GRP94 Antibody (SAA1937) (abinScience Cat# HB250013, RRID:AB_3727701)
_x005F_x005F_x000D_

Forme

Liquid

Tampon de stockage

0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:2000-1:20000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Contexte

Endoplasmin (HSP90B1/GRP94) is a ~92 kDa protein. ATP-dependent chaperone involved in the processing of proteins in the endoplasmic reticulum, regulating their transport. Together with MESD, acts as a modulator of the Wnt pathway by promoting the folding of LRP6, a coreceptor of the canonical Wnt pathway. When associated with CNPY3, required for proper folding of Toll-like receptors. Promotes folding and trafficking of TLR4 to the cell surface. May participate in the unfolding of cytosolic leaderless cargos (lacking the secretion signal sequence) such as the interleukin 1/IL-1 to facilitate their translocation into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) and secretion; the translocation process is mediated by the cargo receptor TMED10.

1. Liu, B. et al. (2013) Proceedings of the National Academy of Sciences of the United States of America 110, 6877-82. PMID: 23572575

2. Ma, M. et al. (2024) Science (New York, N.Y.) 386, 667-672. PMID: 39509507

3. Randow, F. et al. (2001) Nature cell biology 3, 891-6. PMID: 11584270

4. Zhang, M. et al. (2020) Cell 181, 637-652.e15. PMID: 32272059

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human HSP90B1/GRP94 Antibody (SAA1937)

Reférences

Fiche technique

Anti-Human HSP90B1/GRP94 Recombinant Antibody (SAA1937).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

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