Anti-Human HSP90B1/GRP94 Recombinant Antibody (SAA1937) (HB250013)

Name: Anti-Human HSP90B1/GRP94 Recombinant Antibody (SAA1937)
Brand: abinScience
SKU: HB250013
Price: 196 USD
Availability: InStock

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Спецификация:

50ug
100ug
1mg

Количество:

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Обзор
Изображения
Ссылки
Даташит
SDS

Обзор

Каталожный номер

HB250013

Реактивность видов

Human

Применения

ELISA

Хозяинский вид

Mouse

Клоональность

Monoclonal

Изотип

IgG2a, kappa

ID клона

SAA1937

Цель

94 kDa glucose-regulated protein, HSP90B1, gp96 homolog, GRP94, Heat shock protein 90 kDa beta member 1, Endoplasmin, TRA1, Tumor rejection antigen 1, GRP-94

Уровень эндотоксинов

Please contact with the lab for this information.

Чистота

>95% as determined by SDS-PAGE.

Очистка

Protein A/G purified from cell culture supernatant.

Номер доступа

P14625

RRID

Anti-Human HSP90B1/GRP94 Antibody (SAA1937) (abinScience Cat# HB250013, RRID:AB_3727701)
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Форма

Liquid

Буфер хранения

0.01M PBS pH 7.4

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:2000-1:20000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Фон

Endoplasmin (HSP90B1/GRP94) is a ~92 kDa protein. ATP-dependent chaperone involved in the processing of proteins in the endoplasmic reticulum, regulating their transport. Together with MESD, acts as a modulator of the Wnt pathway by promoting the folding of LRP6, a coreceptor of the canonical Wnt pathway. When associated with CNPY3, required for proper folding of Toll-like receptors. Promotes folding and trafficking of TLR4 to the cell surface. May participate in the unfolding of cytosolic leaderless cargos (lacking the secretion signal sequence) such as the interleukin 1/IL-1 to facilitate their translocation into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) and secretion; the translocation process is mediated by the cargo receptor TMED10.

1. Liu, B. et al. (2013) Proceedings of the National Academy of Sciences of the United States of America 110, 6877-82. PMID: 23572575

2. Ma, M. et al. (2024) Science (New York, N.Y.) 386, 667-672. PMID: 39509507

3. Randow, F. et al. (2001) Nature cell biology 3, 891-6. PMID: 11584270

4. Zhang, M. et al. (2020) Cell 181, 637-652.e15. PMID: 32272059

Примечание

For research use only.

Изображения

SDS-PAGE

SDS-PAGE for Anti-Human HSP90B1/GRP94 Antibody (SAA1937)

Ссылки

Даташит

Anti-Human HSP90B1/GRP94 Recombinant Antibody (SAA1937).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

Наборы для анализа