Anti-Human IGFBP-1 Monoclonal Antibody (1A109) (HY471065)

Name: Anti-Human IGFBP-1 Monoclonal Antibody (1A109)
Brand: abinScience
SKU: HY471065
Price: 106 USD
Availability: InStock

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Numéro de catalogue	HY471065
Description	Anti-Human IGFBP1 Monoclonal Antibody (1A109) [1A109] (HY471065) is a mouse monoclonal antibody detecting IGFBP1 in ELISA, IHC, WB. Suitable for Human. Highlights ●Recombinant — Superior batch-to-batch reproducibility with defined sequences. ●Multi-Application — Validated across multiple applications.
Reactivité des espèces	Human
Applications	ELISA, IHC, WB
Espèce hôte	Mouse
Clonalité	Monoclonal
Isotype	IgG1
ID de clone	1A109
Immunogène	Mammalian cells - derived recombinant Human IGFBP1 (Met1-Asn259).
Cible	IGFBP-1, IGFBP1, Insulin-like growth factor-binding protein 1, Placental protein 12, IBP1, IGF-binding protein 1, IBP-1, PP12,
Niveau d'endotoxines	Please contact with the lab for this information.
Pureté	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	P08833
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte	Insulin-like growth factor-binding protein 1 (IGFBP1) is a ~29 kDa protein. Multifunctional protein that plays a critical role in regulating the availability of IGFs such as IGF1 and IGF2 to their receptors and thereby regulates IGF-mediated cellular processes including cell migration, proliferation, differentiation or apoptosis in a cell-type specific manner. Also plays a positive role in cell migration by interacting with integrin ITGA5:ITGB1 through its RGD motif. Mechanistically, binding to integrins leads to activation of focal adhesion kinase/PTK2 and stimulation of the mitogen-activated protein kinase (MAPK) pathway. Regulates cardiomyocyte apoptosis by suppressing HIF-1alpha/HIF1A ubiquitination and subsequent degradation.
Note	For research use only.

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Anti-Human IGFBP-1 Monoclonal Antibody (1A109).pdf

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Anti-Human IGFBP-1 Monoclonal Antibody (1A109) (HY471065)

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