

| Número de catálogo | HY471075 |
|---|---|
| Descripción |
Anti-Human IGFBP1 Monoclonal Antibody (1A110) [1A110] (HY471075) is a mouse monoclonal antibody detecting IGFBP1 in ELISA, IHC, WB. Suitable for Human.
Highlights
|
| Reactividad de especies | Human |
| Aplicaciones | ELISA, IHC, WB |
| Especie huésped | Mouse |
| Clonalidad | Monoclonal |
| Isotipo | IgG1 |
| ID de clon | 1A110 |
| Inmunógeno | Mammalian cells - derived recombinant Human IGFBP1 (Met1-Asn259). |
| Objetivo | IGFBP-1, IGFBP1, Insulin-like growth factor-binding protein 1, Placental protein 12, IBP1, IGF-binding protein 1, IBP-1, PP12, |
| Nivel de endotoxinas | Please contact with the lab for this information. |
| Pureza | >95% as determined by SDS-PAGE. |
| Purificación | Protein A/G purified from cell culture supernatant. |
| Número de acceso | P08833 |
| Forma | Liquid |
| Buffer de almacenamiento | 0.01M PBS pH 7.4. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Fondo | Insulin-like growth factor-binding protein 1 (IGFBP1) is a ~29 kDa protein. Multifunctional protein that plays a critical role in regulating the availability of IGFs such as IGF1 and IGF2 to their receptors and thereby regulates IGF-mediated cellular processes including cell migration, proliferation, differentiation or apoptosis in a cell-type specific manner. Also plays a positive role in cell migration by interacting with integrin ITGA5:ITGB1 through its RGD motif. Mechanistically, binding to integrins leads to activation of focal adhesion kinase/PTK2 and stimulation of the mitogen-activated protein kinase (MAPK) pathway. Regulates cardiomyocyte apoptosis by suppressing HIF-1alpha/HIF1A ubiquitination and subsequent degradation. |
| Nota | For research use only. |

SDS-PAGE for Anti-Human IGFBP1 Monoclonal Antibody (1A110)




Contáctenos para cotizaciones personalizadas, solicitudes en masa y cualquier otro problema.
Correo: [email protected]


Acceso rápido
Contáctenos
+86-027-65523339
Edificio C, No. 666, Calle Shendunsi, Wuhan, 430206, China
中文
English
한국어
日本語
Español
Français
Русский