Anti-Human IL-22 Recombinant Antibody (SAA0391) (HV999107)

Name: Anti-Human IL-22 Recombinant Antibody (SAA0391)
Brand: abinScience
SKU: HV999107
Price: 196 USD
Availability: InStock

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Aperçu

Numéro de catalogue	HV999107
Reactivité des espèces	Human
Applications	ELISA, FCM
Espèce hôte	Mouse
Clonalité	Monoclonal
Isotype	IgG2a, kappa
ID de clone	SAA0391
Cible	Interleukin-22, Cytokine Zcyto18, IL-22, ZCYTO18, IL22, ILTIF, IL-TIF, IL-10-related T-cell-derived-inducible factor
Niveau d'endotoxines	Please contact with the lab for this information.
Pureté	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	Q9GZX6
Forme	Liquid
Tampon de stockage	0.01M PBS, pH 7.4, 0.09% Sodium azide. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Contexte	Interleukin-22 (IL22) is a ~20 kDa protein. Cytokine that plays a critical role in modulating tissue responses during inflammation. Plays an essential role in the regeneration of epithelial cells to maintain barrier function after injury and for the prevention of further tissue damage. Unlike most of the cytokines, has no effect on immune cells. Signals through a heterodimeric receptor composed of two subunits, the specific receptor IL22RA1 which is present on non-immune cells in many organs and the shared subunit IL10RB. Ligation of IL22RA1 with IL22 induces activation of the tyrosine kinases JAK1 and TYK2, which in turn activates STAT3. 1. Brand, S. et al. (2007) American journal of physiology. Gastrointestinal and liver physiology 292, G1019-28. PMID: 17204547 2. Xie, MH. et al. (2000) The Journal of biological chemistry 275, 31335-9. PMID: 10875937 3. Jones, BC. et al. (2008) Structure (London, England : 1993) 16, 1333-44. PMID: 18599299 4. Akil, H. et al. (2015) PloS one 10, e0119872. PMID: 25793261 5. Moniruzzaman, M. et al. (2019) International journal of molecular sciences 20. PMID: 31311100
Note	For research use only.

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SDS-PAGE for Anti-Human IL22 Antibody (SAA0391)

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Anti-Human IL-22 Recombinant Antibody (SAA0391).pdf

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