Home > Products > Antibodies > Flow Cytometry (FACS) Antibodies

Anti-Human IL22 Recombinant Antibody (SAA0391), APC (HV999137)

Datasheet Share product Copy info

Price(USD): $

Spec:

50T
100T

Number:

Contact us

Overview
Images
References
Datasheet
SDS

Overview

Catalog No.	HV999137
Description	Anti-Human IL22 Antibody (SAA0391), APC [SAA0391] (HV999137) is a mouse monoclonal antibody detecting IL22 in ELISA, FCM. Suitable for Human. Highlights ●Flow Cytometry — Validated for flow cytometry applications. ●Fluorescent Label — Direct conjugate for streamlined workflows.
Species reactivity	Human
Applications	ELISA, FCM
Host species	Mouse
Isotype	IgG2a, kappa
Clone ID	SAA0391
Conjugation	APC
Clonality	Monoclonal
Target	Interleukin-22, Cytokine Zcyto18, IL-22, ZCYTO18, IL22, ILTIF, IL-TIF, IL-10-related T-cell-derived-inducible factor
Endotoxin level	Please contact with the lab for this information.
Accession	Q9GZX6
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Background	Interleukin-22 (IL22) is a ~20 kDa protein. Cytokine that plays a critical role in modulating tissue responses during inflammation. Plays an essential role in the regeneration of epithelial cells to maintain barrier function after injury and for the prevention of further tissue damage. Unlike most of the cytokines, has no effect on immune cells. Signals through a heterodimeric receptor composed of two subunits, the specific receptor IL22RA1 which is present on non-immune cells in many organs and the shared subunit IL10RB. Ligation of IL22RA1 with IL22 induces activation of the tyrosine kinases JAK1 and TYK2, which in turn activates STAT3. 1. Brand, S. et al. (2007) American journal of physiology. Gastrointestinal and liver physiology 292, G1019-28. PMID: 17204547 2. Xie, MH. et al. (2000) The Journal of biological chemistry 275, 31335-9. PMID: 10875937 3. Jones, BC. et al. (2008) Structure (London, England : 1993) 16, 1333-44. PMID: 18599299 4. Akil, H. et al. (2015) PloS one 10, e0119872. PMID: 25793261 5. Moniruzzaman, M. et al. (2019) International journal of molecular sciences 20. PMID: 31311100
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

Images

References

Datasheet

Anti-Human IL22 Recombinant Antibody (SAA0391), APC.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

=

Concentration

×

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

×

V₁ (Stock Vol.)

=

Working Solution

C₂ (Working Conc.)

×

V₂ (Working Vol.)

Recommendation

Contact us for custom quotes, bulk requests and any other issues.

Mail: support@abinScience.com

Distributor list

Anti-Human IL22 Recombinant Antibody (SAA0391), APC