Anti-Human IL25/IL17E Recombinant Antibody (ABM109.2) (HV984033)

Name: Anti-Human IL25/IL17E Recombinant Antibody (ABM109.2)
Brand: abinScience
SKU: HV984033
Price: 110 USD
Availability: InStock

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1mg

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Aperçu
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Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HV984033

Reactivité des espèces

Human

Applications

ELISA

Espèce hôte

Mouse

Clonalité

Monoclonal

Isotype

IgG1, kappa

ID de clone

ABM109.2

Cible

Interleukin-25, IL-25, Interleukin-17E, IL-17E, IL25, IL17E, UNQ3120/PRO10272

Niveau d'endotoxines

Please contact with the lab for this information.

Pureté

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

Q9H293

RRID

Anti-Human IL25/IL17E Antibody (ABM109.2) (abinScience Cat# HV984033, RRID:AB_3729202)
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Forme

Liquid

Tampon de stockage

0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:2000-1:20000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Contexte

Interleukin-25 (IL25/IL17E) is a ~20 kDa protein. Cytokine produced by various cells such as eosinophils, T-helper type 2 (Th2) cells or epithelial cells that plays a role in internal safety of adaptive immune responses by regulating cytokine production. Promotes and augments T-helper type 2 responses locally or systemically. Exerts its activity via its receptor composed of IL17RA and IL17RB for signal transduction. In turn, stimulates the JAK2-STAT5A pathway and promotes the secretion of type-2 associated cytokines including IL4, IL9 and IL13. Also induces the release of IL8, and IL6 from eosinophils through the combined activation of MAPK and NF-kappa-B pathways.

1. Wong, CK. et al. (2005) American journal of respiratory cell and molecular biology 33, 186-94. PMID: 15860795

2. Wu, L. et al. (2015) Journal of immunology (Baltimore, Md. : 1950) 194, 4528-34. PMID: 25821217

3. Fort, MM. et al. (2001) Immunity 15, 985-95. PMID: 11754819

Note

For research use only.

Isotype Control

Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21) (MV080207)

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