Anti-Human IL3 Recombinant Antibody (SAA1520) (HY262013)

Name: Anti-Human IL3 Recombinant Antibody (SAA1520)
Brand: abinScience
SKU: HY262013
Price: 110 USD
Availability: InStock

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Цена(USD):

Спецификация:

20ug
50ug
100ug
1mg

Количество:

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Обзор
Изображения
Ссылки
Даташит
SDS

Обзор

Каталожный номер

HY262013

Реактивность видов

Human

Применения

ELISA, WB

Хозяинский вид

Mouse

Клоональность

Monoclonal

Изотип

IgG2a, kappa

ID клона

SAA1520

Цель

IL3, Hematopoietic growth factor, Multipotential colony-stimulating factor, IL-3, Mast cell growth factor, Interleukin-3, P-cell-stimulating factor, MCGF

Уровень эндотоксинов

Please contact with the lab for this information.

Чистота

>95% as determined by SDS-PAGE.

Очистка

Protein A/G purified from cell culture supernatant.

Номер доступа

P08700

RRID

Anti-Human IL3 Antibody (SAA1520) (abinScience Cat# HY262013, RRID:AB_3727281)

Форма

Liquid

Буфер хранения

0.01M PBS pH 7.4

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:2000-1:20000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Фон

Interleukin-3 (IL3) is a ~17 kDa protein. Cytokine secreted predominantly by activated T-lymphocytes as well as mast cells and osteoblastic cells that controls the production and differentiation of hematopoietic progenitor cells into lineage-restricted cells. Also stimulates mature basophils, eosinophils, and monocytes to become functionally activated. In addition, plays an important role in neural cell proliferation and survival. Participates as well in bone homeostasis and inhibits osteoclast differentiation by preventing NF-kappa-B nuclear translocation and activation. Mechanistically, exerts its biological effects through a receptor composed of IL3RA subunit and a signal transducing subunit IL3RB.

1. Guba, SC. et al. (1989) The Journal of clinical investigation 84, 1701-6. PMID: 2556442

2. Okayama, Y. et al. (1993) Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 23, 901-10. PMID: 10779277

3. Hong, L. et al. (2020) Cytokine 136, 155268. PMID: 32889153

4. Luo, XJ. et al. (2012) PloS one 7, e50375. PMID: 23226269

5. Khapli, SM. et al. (2003) Journal of immunology (Baltimore, Md. : 1950) 171, 142-51. PMID: 12816992

6. Broughton, SE. et al. (2018) Nature communications 9, 386. PMID: 29374162

7. López, C. et al. (2017) Journal of cellular biochemistry 118, 1330-1340. PMID: 27862234

Примечание

For research use only.

Изображения

SDS-PAGE

SDS-PAGE for Anti-Human IL3 Antibody (SAA1520)
Bioactivity

Detects recombinant human IL3 (Catalog No: HY262012) in indirect ELISA.
Bioactivity

Detects recombinant human IL3 (Catalog No: HY262011) in indirect ELISA.
Western blot

Western blot analysis was performed using anti-IL3 monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human IL3 (Catalog No: HY262011)