

| Каталожный номер | HV737013 | ||||
|---|---|---|---|---|---|
| Реактивность видов | Human | ||||
| Применения | ELISA | ||||
| Хозяинский вид | Mouse | ||||
| Клоональность | Monoclonal | ||||
| Изотип | IgG2a, kappa | ||||
| ID клона | SAA1623 | ||||
| Цель | Renal carcinoma antigen NY-REN-64, IRAK-4, IRAK4, Interleukin-1 receptor-associated kinase 4 | ||||
| Уровень эндотоксинов | Please contact with the lab for this information. | ||||
| Чистота | >95% as determined by SDS-PAGE. | ||||
| Очистка | Protein A/G purified from cell culture supernatant. | ||||
| Номер доступа | Q9NWZ3 | ||||
| RRID | Anti-Human IRAK4 Antibody (SAA1623) (abinScience Cat# HV737013, RRID:AB_3727384) |
||||
| Форма | Liquid | ||||
| Буфер хранения | 0.01M PBS pH 7.4 Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
||||
| Информация об использовании продукта |
| ||||
| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| Фон | Interleukin-1 receptor-associated kinase 4 (IRAK4) is a ~51 kDa protein. Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens. Involved in Toll-like receptor (TLR) and IL-1R signaling pathways. Is rapidly recruited by MYD88 to the receptor-signaling complex upon TLR activation to form the Myddosome together with IRAK2. Phosphorylates initially IRAK1, thus stimulating the kinase activity and intensive autophosphorylation of IRAK1. Phosphorylates E3 ubiquitin ligases Pellino proteins (PELI1, PELI2 and PELI3) to promote pellino-mediated polyubiquitination of IRAK1. 1. Hoarau, C. et al. (2007) Journal of immunology (Baltimore, Md. : 1950) 179, 4754-65. PMID: 17878374 | ||||
| Примечание | For research use only. |

SDS-PAGE for Anti-Human IRAK4 Antibody (SAA1623)
Свяжитесь с нами для индивидуальных предложений, оптовых запросов и других вопросов.
Почта: [email protected]


+86-027-65523339
Building C, No. 666, Shen Dun Si Lu, Wuhan, 430206, China
中文
English
한국어
日本語
Español
Français
Русский