Anti-Human IRF4 Monoclonal Antibody (1A516) (HS848015)

Name: Anti-Human IRF4 Monoclonal Antibody (1A516)
Brand: abinScience
SKU: HS848015
Price: 106 USD
Availability: InStock

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概要

カタログ番号	HS848015
説明	Anti-Human IRF4 Monoclonal Antibody (1A516) [1A516] (HS848015) is a mouse monoclonal antibody detecting IRF4 in ELISA, IHC, WB. Suitable for Human. Highlights ●Recombinant — Superior batch-to-batch reproducibility with defined sequences. ●Multi-Application — Validated across multiple applications.
種反応性	Human
アプリケーション	ELISA, IHC, WB
宿主種	Mouse
クローン性	Monoclonal
アイソタイプ	IgG
クローンID	1A516
免疫原	E. coli - derived recombinant human IRF4 (Glu130-Glu451).
ターゲット	Interferon regulatory factor 4, IRF-4, Lymphocyte-specific interferon regulatory factor, LSIRF, Multiple myeloma oncogene 1, NF-EM5, IRF4
精製	Protein A/G purified from cell culture supernatant.
アクセッション番号	Q15306
形態	Liquid
保存バッファー	0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
安定性と保存	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景	Interferon regulatory factor 4 (IRF4) is a ~51 kDa protein. Transcriptional activator. Binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8(+) dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes.
注意事項	For research use only.