Anti-Human IRF4 Monoclonal Antibody (1A518) (HS848035)

Name: Anti-Human IRF4 Monoclonal Antibody (1A518)
Brand: abinScience
SKU: HS848035
Price: 106 USD
Availability: InStock

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Overview

Catalog No.	HS848035
Description	Anti-Human IRF4 Monoclonal Antibody (1A518) [1A518] (HS848035) is a mouse monoclonal antibody detecting IRF4 in ELISA, IHC, WB. Suitable for Human. Highlights ●Recombinant — Superior batch-to-batch reproducibility with defined sequences. ●Multi-Application — Validated across multiple applications.
Species reactivity	Human
Applications	ELISA, IHC, WB
Host species	Mouse
Isotype	IgG
Clone ID	1A518
Clonality	Monoclonal
Immunogen	E. coli - derived recombinant human IRF4 (Glu130-Glu451).
Target	Interferon regulatory factor 4, IRF-4, Lymphocyte-specific interferon regulatory factor, LSIRF, Multiple myeloma oncogene 1, NF-EM5, IRF4
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q15306
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background	Interferon regulatory factor 4 (IRF4) is a ~51 kDa protein. Transcriptional activator. Binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8(+) dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes.
Note	For research use only.