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Anti-Human ITSN1 Polyclonal Antibody (HD585014)

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Vista general
Número de catálogoHD585014
Descripción
Anti-Human ITSN1 Polyclonal Antibody (HD585014) is a rabbit polyclonal antibody detecting ITSN1. Suitable for Rat, Human, and Mouse.
Highlights
  • ●Multi-Species — Cross-reactive for translational research.
Reactividad de especiesHuman, Mouse, Rat
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human ITSN1 (Asp1216-Leu1445).
Objetivo ITSN, ITSN1, Intersectin-1, SH3 domain-containing protein 1A, SH3D1A, SH3P17
Nivel de endotoxinas Please contact with the lab for this information.
Purificación Purified by antigen affinity column.
Número de acceso Q15811
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Fondo

Intersectin-1 (ITSN1) is a ~195 kDa protein. Adapter protein that provides a link between the endocytic membrane traffic and the actin assembly machinery. Acts as a guanine nucleotide exchange factor (GEF) for CDC42, and thereby stimulates actin nucleation mediated by WASL and the ARP2/3 complex. Plays a role in the assembly and maturation of clathrin-coated vesicles. Recruits FCHSD2 to clathrin-coated pits. Involved in endocytosis of activated EGFR, and probably also other growth factor receptors.

1. Hussain, NK. et al. (2001) Nature cell biology 3, 927-32. PMID: 11584276
2. Almeida-Souza, L. et al. (2018) Cell 174, 325-337.e14. PMID: 29887380
3. Teckchandani, A. et al. (2012) Molecular biology of the cell 23, 2905-16. PMID: 22648170
4. Jenna, S. et al. (2002) The Journal of biological chemistry 277, 6366-73. PMID: 11744688
Nota For research use only
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Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-Human ITSN1 Polyclonal Antibody

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