Anti-Human JMJD6 IP Recombinant Antibody (SAA0203) (HP634013)

Name: Anti-Human JMJD6 IP Recombinant Antibody (SAA0203)
Brand: abinScience
SKU: HP634013
Price: 191 USD
Availability: InStock

Даташит Поделиться продуктом Копировать информацию

Цена(USD):

Спецификация:

50ug
100ug
1mg

Количество:

Свяжитесь с нами

Обзор
Изображения
Ссылки
Даташит
SDS

Обзор

Каталожный номер

HP634013

Реактивность видов

Human

Применения

ELISA, IF, IP

Хозяинский вид

Mouse

Клоональность

Monoclonal

Изотип

IgG1

ID клона

SAA0203

Цель

Histone arginine demethylase JMJD6, Phosphatidylserine receptor, JmjC domain-containing protein 6, JMJD6, PTDSR, PSR, Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6, Jumonji domain-containing protein 6, Protein PTDSR, Peptide-lysine 5-dioxygenase JMJD6, Lysyl-hydroxylase JMJD6, KIAA0585

Уровень эндотоксинов

Please contact with the lab for this information.

Чистота

>95% as determined by SDS-PAGE.

Очистка

Protein A/G purified from cell culture supernatant.

Номер доступа

Q6NYC1

RRID

Anti-Human JMJD6 IP Antibody (SAA0203) (abinScience Cat# HP634013, RRID:AB_3729737)

Форма

Liquid

Буфер хранения

0.01M PBS pH 7.4

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:2000-1:20000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Фон

Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 is a ~46 kDa protein. Dioxygenase that can both act as a arginine demethylase and a lysyl-hydroxylase. Acts as a lysyl-hydroxylase that catalyzes 5-hydroxylation on specific lysine residues of target proteins such as U2AF2/U2AF65 and LUC7L2. Regulates RNA splicing by mediating 5-hydroxylation of U2AF2/U2AF65, affecting the pre-mRNA splicing activity of U2AF2/U2AF65. Hydroxylates its own N-terminus, which is required for homooligomerization. Plays a role in the regulation of nucleolar liquid-liquid phase separation (LLPS) by post-translationally modifying LIAT1 at its lysine-rich domain which inhibits LIAT1 nucleolar targeting.

1. Chang, B. et al. (2007) Science (New York, N.Y.) 318, 444-7. PMID: 17947579

2. Mantri, M. et al. (2010) Journal of molecular biology 401, 211-22. PMID: 20684070

3. Hahn, P. et al. (2010) PloS one 5, e13769. PMID: 21060799

4. Han, G. et al. (2012) Journal of cellular biochemistry 113, 1663-70. PMID: 22189873

5. Poulard, C. et al. (2014) PloS one 9, e87982. PMID: 24498420

6. Webby, CJ. et al. (2009) Science (New York, N.Y.) 325, 90-3. PMID: 19574390

7. Hong, X. et al. (2010) Proceedings of the National Academy of Sciences of the United States of America 107, 14568-72. PMID: 20679243

8. Konuma, T. et al. (2017) Scientific reports 7, 16272. PMID: 29176719

Примечание

For research use only.

Изображения

SDS-PAGE

SDS-PAGE for Anti-Human JMJD6 IP Antibody (SAA0203)

Ссылки

Даташит

Anti-Human JMJD6 IP Recombinant Antibody (SAA0203).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

Наборы для анализа